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Sandocal 500mg Tablet 10pcs
Calcium Carbonate-
- Primary Uses:
- Heartburn
- Indigestion
- Calcium deficiency
- Hypocalcaemia
- Secondary Uses:
- Hyperphosphatemia
- Calcium supplement
- Stomach upset
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✅ Description:
Sandocal 250 mg or 500 mg Tablet:
- Treatment or prevention of calcium depletion in various conditions including hypoparathyroidism, achlorhydria, chronic diarrhea, vitamin D deficiency, steatorrhea, sprue, pregnancy, lactation, menopause, pancreatitis, renal failure, alkalosis, and hyperphosphataemia.
- Increasingly used for treating hyperphosphataemia in chronic renal failure, continuous ambulatory peritoneal dialysis (CAPD), and hemodialysis.
- Short-term relief of dyspeptic symptoms.
- No longer recommended for the long-term treatment of peptic ulceration.
1000 mg Tablet:
- Management of conditions associated with hyperacidity.
- Fast relief of acid indigestion, heartburn, sour stomach, and upset stomach.
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✔️ Uses of Sandocal 500mg Tablet
Calcium Deficiency Supplement
✔️ How does Sandocal 500mg Tablet work?
- Calcium carbonate can rapidly and effectively neutralize gastric acid.
- Adverse Effects: Activation of calcium-dependent processes, leading to the secretion of gastric and hydrochloric acid.
- Prolonged high doses may cause hypercalcemia, alkalosis, and milk-alkali syndrome.
✔️ Side Effects of Sandocal 500mg Tablet
- Anorexia, nausea, vomiting, constipation, flatulence.
- Hypercalcaemia, metabolic alkalosis, milk-alkali syndrome, tissue calcification.
- Gastric hypersecretion and acid rebound (with prolonged use).
✔️ Quick Suggestions:
- Calcium carbonate has been extensively studied in children and infants with chronic renal failure and is both safe and effective.
- Constipation may be troublesome in elderly patients with renal failure.
- Calcium-containing drugs have been widely used in pregnancy and lactating women.
- Monitoring of serum calcium and phosphate is indicated for elderly patients.
✔️ Pharmacology
- Calcium carbonate reacts with gastric acid to produce salt and water.
- Postulated chemical reaction for Sandocal 500 mg: CaCO3 + 2HCl = CaCl2 + H2O + CO2.
- An increase in gastric pH diminishes the activity of pepsin in gastric secretion.
- Up to 30% of the oral calcium load may be absorbed.
✔️ Dosage & Administration of Sandocal 500mg Tablet
Administration:
- Timing: This may be taken with or without food.
- Enhanced Absorption: Take with meals for better absorption.
- Diet Consideration: Avoid taking with a large amount of fiber-rich food.
Adult Dose:
- Hyperacidity:
- Take 1-2 tablets as needed, up to a maximum of 16 tablets per day.
- Tablets may be sucked or chewed for administration.
- Hyperphosphataemia in Chronic Renal Failure:
- Initial: 2.5 g/day
- Up to 17 g/day in divided doses.
Renal Dose:
- Renal impairment (CrCl < 25 ml/min): Dosage adjustments may be needed based on serum calcium levels.
✔️ Interaction
- Co-administration with thiazide diuretics or vitamin D may lead to milk-alkali syndrome and hypercalcaemia.
- Decreased absorption with corticosteroids.
- Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn, and calcium-channel blockers.
- Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication.
✔️ Contraindications
- Patients with calcium renal calculi or a history of renal calculi.
- Hypercalcaemia.
- Hypophosphataemia.
- Patients with suspected digoxin toxicity.
✔️ Pregnancy & Lactation
- Pregnancy category: C.
- Lactation: Safe; crosses the placenta and appears in breast milk.
✔️ Precautions & Warnings
- Renal impairment.
- Hypoparathyroid disease.
- Hypercalcemia-associated diseases.
- Caution in patients with a history of kidney stones.
- Calcium absorption is impaired in achlorhydria; use an alternate salt and take it with food.
- Lactation: Safe; crosses the placenta and appears in breast milk.
✔️ Storage Conditions
Store in a cool, dry place in controlled room temperature.
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